cdc42/Rac Antibody

• Catalog number
  3080-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  cdc42/Rac
• Target Alternative Name
  CDC42Hs , G25K
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, bovine
• Immunogen Sequence
  Synthetic peptides surrounding amino acid 144 of human cdc42
• Accession
  NP_426359.1
• Gene Id
  998
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) affinity purified rabbit anti-cdc42 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Application And Usages
  Western blotting (0.5-4 µg/ml) and in Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. The antibody detects cdc42 of human, mouse, rat, and bovine origins.
• Description
  cdc42/Rac belongs to the superfamily of small GTPases that are structurally linked to the proto-oncogene product p21ras and are important for the control of cell growth and differentiation as well as for intracellular organization. Cdc42/Rac is an important upstream regulator of the protein kinase cascade that controls the SAPK/JNK and p38 activity. Recent data also sμggest that constitutive active forms of cdc42 can induce apoptosis throμgh a mechanism requiring signaling throμgh SAPK/JNK.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  cdc42/Rac  
• Gene symbol
  ARHGEF6, PAK1, PAK4
• Short name
  cdc42/Rac Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  cellular division cycle 42 (GTP binding protein, 25kDa)/Rac (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  cell division cycle 42 (GTP binding protein, 25kDa), CDC42Hs and G25K, CDC42 and IDBG-93614 and ENSG00000070831 and 998, identical protein binding, Cell surfaces, Cdc42 and IDBG-198471 and ENSMUSG00000006699 and 12540, BT.56113 and IDBG-645532 and ENSBTAG00000001700 and 532712

Gene info

• Identity
  HGNC:685
• Gene
  ARHGEF6
• Long gene name
  Rac/Cdc42 guanine nucleotide exchange factor 6
• Synonyms gene
  • MRX46
• Synonyms gene name
  • mental retardation, X-linked 46
  • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
• Synonyms
  • alphaPIX
  • Cool-2
  • KIAA0006
  • alpha-PIX
  • Cool2
  • αPix
• Synonyms name
  • Rac/Cdc42 guanine exchange factor (GEF) 6
  • PAK-interacting exchange factor, alpha
  • rho guanine nucleotide exchange factor 6
• GenBank acession
  • D13631
• Locus
  Xq26.3
• Discovery year
  2000-07-27
• Entrez gene record
  9459
• Pubmed identfication
  • 7584048
  • 9659915
• RefSeq identity
  • NM_004840
• Classification
  • Pleckstrin homology domain containing
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000022518
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:8590
• Gene
  PAK1
• Long gene name
  p21 (RAC1) activated kinase 1
• Synonyms gene name
  • p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
  • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
  • p21 protein (Cdc42/Rac)-activated kinase 1
• Synonyms name
  • STE20 homolog, yeast
• GenBank acession
  • U51120
• Locus
  11q13.5-q14.1
• Discovery year
  1997-12-05
• Entrez gene record
  5058
• Pubmed identfication
  • 8805275
  • 9533029
• RefSeq identity
  • NM_002576
• VEGA ID
  OTTHUMG00000165138

Gene info

• Identity
  HGNC:16059
• Gene
  PAK4
• Long gene name
  p21 (RAC1) activated kinase 4
• Synonyms gene name
  • p21(CDKN1A)-activated kinase 4
  • p21 protein (Cdc42/Rac)-activated kinase 4
• GenBank acession
  • AJ011855
• Locus
  19q13.2
• Discovery year
  2001-07-12
• Entrez gene record
  10298
• Pubmed identfication
  • 9822598
  • 10461188
• VEGA ID
  OTTHUMG00000182800

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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