anti-p38 MAPK (phospho Thr180 / Tyr182) Antibody

  • Catalog number
    XPS-1020
  • Price
    Please ask
  • Size
    0.1 mL
  • Gene info
    The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one these kinases and it is activated by both inflammatory cytokines and by stress. The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.
  • Gene names
    RK, Hog, p38, CRK1, CSBP, Exip, Mxi2, CSPB1, Csbp1, Csbp2, Prkm14, Prkm15, Sapk2A, p38Hog, p38alpha, MAP kinase 14
  • Antibodie s label
    unlabelled serum
  • Purity
    Affinity Purified
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Spicific to
    p38 MAPK antibody is specific for the ~39k p38 protein phosphorylated at Thr180/Tyr182.
  • Antigen
    p38 MAPK (Thr180/Tyr182) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Thr180/Tyr182 of p38.
  • Immuno application
    Western Blot
  • Antibody advice
    Immunolabeling in Western blots of C-6 glioma cells prepared with anisomycin treatment is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Applications include Immunoblotting (DB) and Western Blots (WB). Immunohistochemistry (IHC): not yet determined. Human, mouse and rat have 100% amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.
  • Suspention pH azide
    100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
  • Keep at
    For long term storage –80 grades C is recommended, but shorter term storage at –20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    2499601
  • Ncbi nr
    P70618
  • KDa
    39
  • Vial with antibody
    in solution
  • NCBI GENE nr
    81649
  • GENE symbol
    Mapk14
  • Antigene name
    mitogen activated protein kinase 14
  • Source
    Rattus norvegicus
  • Protein nr
    P70618
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    p38   MAPK   phospho   Thr180   Tyr182  
  • Short name
    anti-p38 MAPK (phospho Thr180 / Tyr182) Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody top38 MAPK (phosphorilated Thr180 / Tyr182) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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