OTP Antibody, ALEXA FLUOR 594
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Catalog number
bs-11920R-A594
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Price
Please ask
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Size
100ul
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Long name
OTP Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
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Also known as
Anti-OTP PAb ALEXA FLUOR 594
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 594
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
OTP
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Specificity
This is a highly specific antibody against OTP.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTP
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates. OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily. OTP is expressed in neurons, which give rise to the paraventricular (PVN), supraoptic (SON), anterior periventricular (aPV) and arcuate (ARN) nuclei. Containing a homeobox DNA-binding domain and a OAR domain, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells. At early embryonic stages in mice, the expression of SIM2 is downregulated in the absence of OTP, indicating a potential role for OTP as an upstream regulator of SIM2. OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
590nm/617nm
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Synonyms
MGC3161; orthopedia homeobox; orthopedia homolog; OTP_HUMAN.
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Properties
For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR® 594
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Conjugated
Alexa conjugate 1
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French translation
anticorps
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Gene target
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Gene symbol
OTP
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Short name
Anti-OTP
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 594
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Alternative name
OTP Polyclonal Antibody, ALEXA FLUOR 594
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
orthopedia homeobox
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Synonyms gene name
- orthopedia homolog (Drosophila)
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Locus
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Discovery year
1999-02-09
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Entrez gene record
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Pubmed identfication
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Classification
- PRD class homeoboxes and pseudogenes
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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