OTP Antibody, ALEXA FLUOR 594

  • Catalog number
    bs-11920R-A594
  • Price
    Please ask
  • Size
    100ul
  • Long name
    OTP Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-OTP PAb ALEXA FLUOR 594
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 594
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    OTP
  • Specificity
    This is a highly specific antibody against OTP.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTP
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates. OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily. OTP is expressed in neurons, which give rise to the paraventricular (PVN), supraoptic (SON), anterior periventricular (aPV) and arcuate (ARN) nuclei. Containing a homeobox DNA-binding domain and a OAR domain, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells. At early embryonic stages in mice, the expression of SIM2 is downregulated in the absence of OTP, indicating a potential role for OTP as an upstream regulator of SIM2. OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    590nm/617nm
  • Synonyms
    MGC3161; orthopedia homeobox; orthopedia homolog; OTP_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Gene target
    OTP  
  • Gene symbol
    OTP
  • Short name
    Anti-OTP
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    OTP Polyclonal Antibody, ALEXA FLUOR 594
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
    OTP
  • Long gene name
    orthopedia homeobox
  • Synonyms gene name
    • orthopedia homolog (Drosophila)
  • Locus
  • Discovery year
    1999-02-09
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • PRD class homeoboxes and pseudogenes
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee