anti Nucleophosmin Antibody

anti Nucleophosmin Antibody is available 2 times from Biovision labs

6663-30T | anti-Nucleophosmin Antibodysize: Nucleophosmin Antibody | 170.34 USD

Ajax processing

6663-100 | anti-Nucleophosmin Antibodysize: Nucleophosmin Antibody | 391.67 USD

Ajax processing
  • Target of this antibody:
    Nucleophosmin
  • Alternative names of antibody target:
    Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM, NPM1
  • Background information:
    Nucleophosmin is a nucleus protein which belongs to the nucleoplasmin family. It is a nucleolar phosphoprotein that shuttles between the nucleus and cytoplasm during the cell cycle. Nucleophosmin / NPM1 is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53 / p53 and ARF. Subcellular localization of Nucleophosmin / NPM1 appears to be strongly correlated with NPM1 functions and cell proliferation. It is phosphorylated mainly at its central acidic domain by several upstream kinases, and its phosphorylation appears to be involved in regulating its functions in ribosome biogenesis and centrosome duplication. Nucleophosmin / NPM1 binds ribosome presumably to drive ribosome nuclear export. It is associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Nucleophosmin / NPM1 acts as a chaperonin for the core histones H3, H2B and H4. Nucleophosmin / NPM1 may act as a licensing factor to maintain proper centrosome duplication and that the Ran/CRM1 nucleocytoplasmic complex regulates local trafficking of Nucleophosmin / NPM1 to centrosomes by interacting through its nuclear export sequence motif.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • This antibody reacts with:
    Human
  • Immunogene sequence:
    Recombinant human Nucleophosmin (Cat # 7258)
  • Concentration of antibody:
    0.5 mg/ml
  • Form of antibody:
    Liquid
  • Purification method:
    Affinity Purified Antibody
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Recommended usage:
    Western blot: 1-4 µg/ml.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-Nucleophosmin Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-Nucleophosmin (Antibody to)
  • Alternative technique
    antibodies
Simillar products
Supplier:proscience
Price:208.58USD
Supplier:aviva
Price:268.84USD
Supplier:Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price:405.75USD
Supplier:aviva
Price:362.70USD
Supplier:Cloud Clone Corp
Price:1 842.49USD
Supplier:MBS Polyclonals
Price:307.08USD
Supplier:MyBioSource
Price:0.00USD
Supplier:MyBioSource
Price:0.00USD
Supplier:bioma
Price:362.70USD
Supplier:genways bulk
Price:0.00USD
Supplier:SFC
Price:0.00USD
Supplier:aviva
Price:491.33USD
Supplier:aviva
Price:387.04USD
Supplier:MyBioSource
Price:615.32USD
Supplier:MyBioSource
Price:0.00USD
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
anti Nucleophosmin Antibody - Gentaur.com
Contact
Chat with gentaur.com employee