Noxa Antibody

• Catalog number
  3665-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  Noxa
• Target Alternative Name
  PMAIP1 , NOXA , APR
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 100 of human Noxa
• Accession
  AAH32663
• Gene Id
  5366
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  30 µg (0.2 mg/ml) protein A purified rabbit anti-Noxa polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mainly ~16 kDa band in human, mouse and rat samples. A ~34 kDa band is also detected to the lesser extent. Reactivity to other species has not been tested.
• Description
  Noxa is a BH3-only member of the Bcl-2 family. Expression of Noxa gene involves direct activation of its promotor by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53-deficient thymocytes. Coimmunoprecipitation data sμggest that Noxa protein may interact with proteins belonging to the Bcl-2 family, such as Bcl-xL and Mcl-1. Blocking the endogenous Noxa induction results in the suppression of apoptosis. These sμggest Noxa may represent a candidate mediator of p53-induced apoptosis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Noxa  
• Gene symbol
  PMAIP1
• Short name
  Noxa Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Noxa (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9108
• Gene
  PMAIP1
• Long gene name
  phorbol-12-myristate-13-acetate-induced protein 1
• Synonyms
  • APR
  • NOXA
• GenBank acession
  • D90070
• Locus
  18q21.32
• Discovery year
  1991-08-12
• Entrez gene record
  5366
• Pubmed identfication
  • 2398525
  • 12879012
• RefSeq identity
  • NM_021127
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000132765

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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