anti-NFX1 Antibody

• Catalog number
  27-238
• Price
  Please ask
• Size
  50 ug

• Gene info
  MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
• Gene names
  NFX1, DKFZp779G2416, MGC20369, NFX2, Tex42, TEG-42
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFX1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  NFX1 antibody can be used for detection of NFX1 by ELISA at 1:312500. NFX1 antibody can be used for detection of NFX1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store NFX1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  21361137
• Ncbi nr
  NP_002495
• KDa
  124 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  4799
• GENE symbol
  NFX1
• Antigene name
  nuclear transcription factor, X-box binding 1
• Source
  Homo sapiens
• Protein nr
  Q12986
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NFX1  
• Gene symbol
  NFX1
• Short name
  anti-NFX1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNFX1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  nuclear transcription factor, X-box binding 1, NFX2 and TEG-42 and Tex42, NFX1 and IDBG-57493 and ENSG00000086102 and 4799, poly(A) RNA binding, nuclei, Nfx1 and IDBG-136741 and ENSMUSG00000028423 and 74164, NFX1 and IDBG-635780 and ENSBTAG00000012385 and 515680

Gene info

• Identity
  HGNC:7803
• Gene
  NFX1
• Long gene name
  nuclear transcription factor, X-box binding 1
• Synonyms
  • NFX2
  • MGC20369
  • Tex42
  • TEG-42
• GenBank acession
  • U19759
• Locus
  9p12
• Discovery year
  1998-05-26
• Pubmed identfication
  • 7964459
  • 2511169
  • 12047746
• Classification
  • PHD finger proteins
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000019772

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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