anti-NALP4 Antibody

• Catalog number
  5957
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  NALP4 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-kB induction by TNF-a; and IL-1β, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-kB induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TRAF2, TRAF6, RIP, and IRAK2, as well as the IKK-alpha and IKK-beta, suggesting that NALP4 is critical in modulating NF-kB activity.
• Gene names
  NALP4 Antibody: CT58, PAN2, RNH2, NALP4, PYPAF4, CLR19.5, NACHT, LRR and PYD domains-containing protein 4, PAAD and NACHT-containing protein 2, CT58
• Antibodie s label
  unlabelled serum
• Purity
  NALP4 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  NALP4 antibody was made against a 13 amino acid synthetic peptide near the center of human NALP4.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  NALP4 antibody can be used for detection of NALP4 by Western blot at 1 ug/mL.
• Suspention pH azide
  NALP4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  NALP4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  17064172
• Ncbi nr
  AAL35293
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  147945
• GENE symbol
  NLRP4
• Antigene name
  NLR family, pyrin domain containing 4
• Source
  Homo sapiens
• Protein nr
  Q96MN2
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NALP4  
• Gene symbol
  NLRP4
• Short name
  anti-NALP4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNALP4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22943
• Gene
  NLRP4
• Long gene name
  NLR family pyrin domain containing 4
• Synonyms gene
  • NALP4
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 4
• Synonyms
  • PYPAF4
  • FLJ32126
  • PAN2
  • RNH2
  • CLR19.5
  • CT58
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4
  • cancer/testis antigen 58
• GenBank acession
  • AF479747
• Locus
  19q13.43
• Discovery year
  2003-10-28
• Entrez gene record
  147945
• Pubmed identfication
  • 12563287
  • 12019269
• RefSeq identity
  • NM_134444
• Classification
  • NLR family
  • Pyrin domain containing
• VEGA ID
  OTTHUMG00000181734

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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