anti-MYST1 Antibody [8C4C4]

  • Catalog number
    32-197
  • Price
    Please ask
  • Size
    0.1 mL
  • Gene info
    MYST1 (MYST histone acetyltransferase 1,MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone.
  • Gene names
    MOF, MYST1, PP7073, Lysine acetyltransferase 8, MYST-1, MOF, hMOF, ZC2HC8
  • Antibodie s label
    unlabelled serum
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    8C4C4
  • Immunoglobulin
    IgG2b
  • Antigen
    Ni-NTA purified truncated recombinant MYST1-trx expressed in E. Coli strain BL21 (DE3).
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
  • Suspention pH azide
    Ascitic fluid containing 0.03% sodium azide.
  • Keep at
    MYST1 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    68565938
  • Ncbi nr
    Q9H7Z6
  • NCBI GENE nr
    84148
  • GENE symbol
    KAT8
  • Antigene name
    K(lysine) acetyltransferase 8
  • Source
    Homo sapiens
  • Protein nr
    Q9H7Z6
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MYST1   [8C4C4]  
  • Gene symbol
    KAT8
  • Short name
    anti-MYST1 Antibody [8C4C4]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toMYST1 (antibody to-) [8C4C4]
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    lysine acetyltransferase 8
  • Synonyms gene
  • Synonyms gene name
    • MYST histone acetyltransferase 1
    • K(lysine) acetyltransferase 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2002-08-06
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • MSL histone acetyltransferase complex
    • NSL histone acetyltransferase complex
    • Zinc fingers C2HC-type
    • MYST type domain containing lysine acetyltransferases
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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