Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) Mouse Monoclonal Antibody

• Catalog number
  MBS438719
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Smooth Muscle Myosin Heavy Chain (SM-MHC)]
• Products_name_syn
  [AAT4; Myosin heavy chain 11 (MYH11); Myosin heavy chain 11 smooth muscle; Smooth muscle myosin heavy chain 11; Myosin-11; SM1; SM2; SMHC; SMMHC]
• Other_names
  [myosin-11 isoform SM2B; Myosin-11; myosin-11; myosin heavy chain 11; Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC]
• Products_gene_name
  [MYH11]
• Other_gene_names
  [MYH11; MYH11; AAT4; FAA4; SMHC; SMMHC; KIAA0866]
• Clonality
  Monoclonal
• Clone
  [MYH11/923]
• Reactivity
  Human, Rat. Predicted to have broad species reactivity
• Specificity
  Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  For cells, cell lines and tissues in culture till half confluency.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Smooth   Muscle   Myosin   Heavy   Chain   SM-MHC   Leiomyosarcoma   Myoepithelial   Monoclonal  
• Gene symbol
  MYH11, SNRPE, SNRPF, SNRPG, SNRPD1, SNRPD3, CNN1, SNRPD2, EGLN1, SNRPB
• Short name
  Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial ) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, kappa
• Species
  Mouse, Mouses
• Alternative name
  Smooth Muscle Myosin Heavy epitope (SM-Major histocompabitility complex) (Leiomyosarcoma & Myoepithelial cellular detection labelled) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Tissue
  cell, muscle

Gene info

• Identity
  HGNC:7569
• Gene
  MYH11
• Long gene name
  myosin heavy chain 11
• Synonyms gene name
  • myosin, heavy polypeptide 11, smooth muscle
• Synonyms
  • SMMHC
  • SMHC
• GenBank acession
  • X69292
• Locus
  16p13.11
• Discovery year
  1991-09-13
• Entrez gene record
  4629
• Pubmed identfication
  • 7684189
• RefSeq identity
  • NM_001040113
• Classification
  • Myosin heavy chains, class II
• VEGA ID
  OTTHUMG00000129935
• Locus Specific Databases
  • LRG_1401

Gene info

• Identity
  HGNC:11161
• Gene
  SNRPE
• Long gene name
  small nuclear ribonucleoprotein polypeptide E
• Synonyms
  • Sm-E
• GenBank acession
  • M37716
• Locus
  1q32.1
• Discovery year
  1988-11-28
• Entrez gene record
  6635
• Pubmed identfication
  • 1835977
  • 2143747
• RefSeq identity
  • NM_003094
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000035985

Gene info

• Identity
  HGNC:11162
• Gene
  SNRPF
• Long gene name
  small nuclear ribonucleoprotein polypeptide F
• Synonyms
  • Sm-F
• GenBank acession
  • X85372
• Locus
  12q23.1
• Discovery year
  1990-06-13
• Entrez gene record
  6636
• Pubmed identfication
  • 7744013
• RefSeq identity
  • NM_003095
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000170351

Gene info

• Identity
  HGNC:11163
• Gene
  SNRPG
• Long gene name
  small nuclear ribonucleoprotein polypeptide G
• Synonyms
  • Sm-G
• GenBank acession
  • X85373
• Locus
  2p13.3
• Discovery year
  1990-06-13
• Entrez gene record
  6637
• Pubmed identfication
  • 7744013
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000129670

Gene info

• Identity
  HGNC:11158
• Gene
  SNRPD1
• Long gene name
  small nuclear ribonucleoprotein D1 polypeptide
• Synonyms gene
  • SNRPD
• Synonyms gene name
  • small nuclear ribonucleoprotein D1 polypeptide (16kD)
  • small nuclear ribonucleoprotein D1 polypeptide 16kDa
• Synonyms
  • HsT2456
  • Sm-D1
• GenBank acession
  • L36188
• Locus
  18q11.2
• Discovery year
  1990-06-13
• Entrez gene record
  6632
• Pubmed identfication
  • 7527560
  • 1701240
• RefSeq identity
  • NM_006938
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000178934

Gene info

• Identity
  HGNC:11160
• Gene
  SNRPD3
• Long gene name
  small nuclear ribonucleoprotein D3 polypeptide
• Synonyms gene name
  • small nuclear ribonucleoprotein D3 polypeptide (18kD)
  • small nuclear ribonucleoprotein D3 polypeptide 18kDa
• Synonyms
  • SMD3
  • Sm-D3
• GenBank acession
  • U15009
• Locus
  22q11.23
• Discovery year
  1995-04-26
• Entrez gene record
  6634
• Pubmed identfication
  • 1701240
  • 7527560
• RefSeq identity
  • NM_004175
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000150727

Gene info

• Identity
  HGNC:2155
• Gene
  CNN1
• Long gene name
  calponin 1
• Synonyms gene name
  • calponin 1, basic, smooth muscle
• Synonyms
  • SMCC
  • Sm-Calp
• GenBank acession
  • U37019
• Locus
  19p13.2
• Discovery year
  1996-08-16
• Entrez gene record
  1264
• Pubmed identfication
  • 8526917
  • 9332369
• RefSeq identity
  • NM_001299
• VEGA ID
  OTTHUMG00000182033

Gene info

• Identity
  HGNC:11159
• Gene
  SNRPD2
• Long gene name
  small nuclear ribonucleoprotein D2 polypeptide
• Synonyms gene
  • SNRPD1
• Synonyms gene name
  • small nuclear ribonucleoprotein D2 polypeptide (16.5kD)
  • small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
• Synonyms
  • Sm-D2
• Synonyms name
  • snRNP core protein D2
• Locus
  19q13.2-q13.3
• Discovery year
  1990-06-13
• Entrez gene record
  6633
• Pubmed identfication
  • 7527560
  • 1701240
• RefSeq identity
  • NM_004597
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000182130

Gene info

• Identity
  HGNC:1232
• Gene
  EGLN1
• Long gene name
  egl-9 family hypoxia inducible factor 1
• Synonyms gene
  • C1orf12
• Synonyms gene name
  • EGL nine (C.elegans) homolog 1
  • egl nine homolog 1 (C. elegans)
  • egl-9 family hypoxia-inducible factor 1
• Synonyms
  • SM-20
  • PHD2
  • ZMYND6
  • HIFPH2
• Synonyms name
  • HIF prolyl hydroxylase 2
• GenBank acession
  • AJ310543
• Locus
  1q42.2
• Discovery year
  2000-06-16
• Entrez gene record
  54583
• Pubmed identfication
  • 11056053
• RefSeq identity
  • NM_022051
• Classification
  • Zinc fingers MYND-type
• VEGA ID
  OTTHUMG00000038027

Gene info

• Identity
  HGNC:11153
• Gene
  SNRPB
• Long gene name
  small nuclear ribonucleoprotein polypeptides B and B1
• Synonyms gene
  • SNRPB1
• Synonyms
  • COD
  • SmB/SmB'
  • Sm-B/B'
  • snRNP-B
• Locus
  20p13
• Discovery year
  1988-11-28
• Entrez gene record
  6628
• Pubmed identfication
  • 1376292
• Classification
  • Small nucleolar RNA protein coding host genes
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000031694

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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