anti-MYD88 Antibody

• Catalog number
  2127
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  MYD88 Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.
• Gene names
  MYD88 Antibody: MYD88D
• Antibodie s label
  unlabelled serum
• Purity
  MYD88 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  MD88 antibody was made against an 18 amino acid peptide near the carboxy terminus of human MD88.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  MYD88 antibody can be used for detection of MyD88 by Western blot 0.5 ug/mL. For immunohistochemistry use a concentration of 4 ug/mL. For immunofluorescence and immunocytochemistry use a concentration of 5 ug/mL.
• Suspention pH azide
  MYD88 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  MYD88 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  1763090
• Ncbi nr
  U70451
• KDa
  Aprox: 35 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  4615
• GENE symbol
  MYD88
• Antigene name
  myeloid differentiation primary response gene (88)
• Source
  Homo sapiens
• Protein nr
  U70451
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MYD88  
• Gene symbol
  MYD88
• Short name
  anti-MYD88 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMYD88 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  myeloid differentiation primary response 88, MYD88D, MYD88 and IDBG-25713 and ENSG00000172936 and 4615, TIR domain binding, Plasma membranes, Myd88 and IDBG-204565 and ENSMUSG00000032508 and 17874, MYD88 and IDBG-644299 and ENSBTAG00000000563 and 444881

Gene info

• Identity
  HGNC:7562
• Gene
  MYD88
• Long gene name
  MYD88 innate immune signal transduction adaptor
• Synonyms gene name
  • myeloid differentiation primary response gene (88)
  • myeloid differentiation primary response 88
• GenBank acession
  • U84408
• Locus
  3p22.2
• Discovery year
  1997-12-23
• Entrez gene record
  4615
• Pubmed identfication
  • 9013863
• RefSeq identity
  • NM_002468
• Classification
  • TIR domain containing
  • My-T-BRC complex
• VEGA ID
  OTTHUMG00000131083
• Locus Specific Databases
  • LRG_157

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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