Anti-Mouse EphA3 is available 1 time from Reliatech antibodies labs
- Gene NameEphA3
- Species ReactivityMouse (Mus musculus)
- SynonymsEpha3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086
- DescriptionThis is a highly purified antibody with strong binding affinity towards the antigen that it has been risen against.Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in.
- Storage and handlingLyophilized antibodies can be shipped at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage. Reconstituted lyophilised and antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius. Generally, it is recomended for long term storage (up to one year) 25-50% glycerol or ethylene glycol to be added and the vial must be stored at -20°C.
- AdvisoryIn order to retain the quality and the affinity of the antibodies unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
- TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
- Latin nameMus musculus
- Gene target
- Short nameAnti-Mouse EphA3
- TechniqueMouse, anti
- Alternative nameantibody to-Mouse EPH receptor A3
- Alternative techniqueantibodies
- Alternative to gene targetEPH receptor A3, EK4 and ETK and ETK1 and HEK and HEK4 and TYRO4, EPHA3 and IDBG-45928 and ENSG00000044524 and 2042, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005003 and ephrin receptor activity and molecular function this GO :0005004 and GPI-linked ephrin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005769 and early endosome and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0010717 and regulation of epithelial to mesenchymal transition and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0032319 and regulation of Rho GTPase activity and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0048013 and ephrin receptor signaling pathway and biological process this GO :0051893 and regulation of focal adhesion assembly and biological process this GO :0070507 and regulation of microtubule cytoskeleton organization and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0097155 and fasciculation of sensory neuron axon and biological process this GO :0097156 and fasciculation of motor neuron axon and biological process, transferase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005003: ephrin receptor activity and also this GO :0005004: GPI-linked ephrin receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, transferring phosphorus-containing groups, this GO :0004672: protein kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005003: ephrin receptor activity, this GO :0005004: GPI-linked ephrin receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferring phosphorus-containing groups, Extracellular, Epha3 and IDBG-170437 and ENSMUSG00000052504 and 13837, BT.30722 and IDBG-630811 and ENSBTAG00000006811 and 537951
103-M164 | Anti-Mouse EphA3size: 100ug | 413.31 USD
- Catalog number103-M164
- Price413.31 USD
1. Gene info
- Long gene nameEPH receptor A3
- Synonyms gene
- Synonyms gene name
- GenBank acession
- Discovery year1993-06-23
- Entrez gene record
- Pubmed identfication
- RefSeq identity
- Sterile alpha motif domain containing
- Fibronectin type III domain containing
- EPH receptors
- Havana BLAST/BLAT
- ConceptScope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedin axial nerves, establishment of discrete afferent & efferent pathways depends on signaling between coextending sensory & motor projections; the axon-axon interactions require motor axonal EphA3/EphA4 activated by cognate sensory axonal ephrin-A ligandsRetrograde labeling studies in EphA3(-/-) embryos and adults indicate that EphA3 is not necessary to direct motor axons to axial muscle targets.results indicate that EphA3 plays a crucial role in the development and morphogenesis of the cells that give rise to the atrioventricular valves and septa.EphA3 receptor localized only in neuronal cells of the hippocampus was enhanced without transcriptional regulation during synaptic plasticity through activation of the nicotinic acetylcholine receptor.ephrinA5/EphA3 triggers proteolysis of the neural cell adhesion molecule (NCAM) by the metalloprotease a disintegrin and metalloprotease (ADAM)10 to promote growth cone collapse in neurons from mouse neocortex.Mutations in EPHA family genes may cause cleft lip/palate with functional redundancy between family members perhaps at play.Ephrin-A3 has a role in promoting and maintaining slow muscle fiber identity during postnatal development and reinnervationstudy delineates a mechanism in which NCAM promotes ephrin-A5-dependent clustering of EphA3 through interaction of the NCAM Ig2 domain and the EphA3 CRD, stimulating EphA3 autophosphorylation and RhoA signaling necessary for growth cone repulsion in GABAergic interneurons in vitro, which may extend to remodeling of axonal terminals of interneurons in vivo.
- Gene ontology - Biological process
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
Supplier:Bioss Polyclonal Antibodies