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Alternative name1
Anti-RABBIT ANTI MOUSE DACT1
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Alternative name2
RABBIT ANTI Murine DACT1
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Alternative name3
Lapin ANTI Mus musculus DACT1
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Alternative name4
DACT1
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Alternative name5
N/A
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Other names
dapper homolog 1 isoform 2; Dapper homolog 1; dapper homolog 1; dapper 1; frodo homolog; thymus expressed gene 3; dapper antagonist of catenin 1; thymus-expressed novel gene 3 protein; dapper homolog 1, antagonist of beta-catenin (xenopus); Dapper antagonist of catenin 1; Frodo homolog; MDpr1; Thymus-expressed novel gene 3 protein
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Gene name
DACT1
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Gene name synonims
N/A
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Other gene names
Dact1; Dact1; Frd1; FRODO; MDpr1; MTNG3; DAPPER; Frodo1; THYEX3; DAPPER1; AI115603; 4921528D17Rik; Thyex3
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Mouse
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Specificity and cross reactivity
DACT1 This item recognises mouse Dact1 (Dapper homolog 1), an intracellular protein and member of the dapper family, which acts as a positive regulator of the signalling pathways of Dishevelled 2 (DVL2), a cytoplasmic protein which plays a pivotal role in Wnt signalling during vertebrate development. Dact1 is involved in enhancement of the transcriptional activation of target genes of the Wnt signalling pathway, through its intracellular co-localization with DVL2 and inhibition of the degradation of CTNNB1/beta-catenin. Studies have shown that mice homozygous for mutations in Dact1, display malformations involving the spine, genitourinary system and distal digestive tract, which was traced to disrupted germ-layer morphogenesis at the primitive streak
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 1.0mg/ml
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Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested for
Western Blot (WB)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps