anti Mcl 1 Antibody

anti Mcl 1 Antibody is available 2 times from Biovision labs

3035-30T | anti-Mcl-1 Antibodysize: Mcl-1 Antibody | 173.12 USD

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3035-100 | anti-Mcl-1 Antibodysize: Mcl-1 Antibody | 372.15 USD

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  • Target of this antibody:
    Mcl-1
  • Alternative names of antibody target:
    MCL1L, mcl1/EAT, MGC1839, MGC104264, TM, MCL1S, EAT
  • Background information:
    Mcl-1 (Myeloid cell leukemia-1) is a 37 kDa Bcl-2-related protein with an apparent molecular weight of 43 kDa on SDS-PAGE. Mcl-1 was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-β1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • This antibody reacts with:
    Human, mouse, rat, monkey
  • Immunogene sequence:
    Synthetic peptide corresponding to residues surrounding amino acid 131 of human Mcl-1
  • Concentration of antibody:
    0.2 mg/ml
  • Form of antibody:
    Liquid
  • Purification method:
    Affinity purified
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunoprecipitation, Immunohistochemistry
  • Recommended usage:
    Western blot analysis (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml), and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-Mcl-1 Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-Mcl-1 (Antibody to)
  • Alternative technique
    antibodies
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