MBD4 Antibody

  • Catalog number
    3056-30T
  • Price
    Please ask
  • Size
    30 µg
  • Antibody Target
    MBD4
  • Target Alternative Name
    MBD4, Methyl-CpG-binding domain protein 4, Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein, MBD4, Mismatch-specific DNA N-glycosylase, MED1
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse, rat
  • Immunogen Sequence
    Synthetic peptide surrounding amino acid 474 of mouse MBD4
  • Accession
    O95243
  • Gene Id
    8930
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    30 µg (0.5 mg/ml) affinity purified rabbit anti-MBD4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
  • Purification
    Affinity purified
  • Application
    Western blot
  • Positive Control
    Jurkat cell lysates
  • Application And Usages
    The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually.
  • Description
    MBD4 (methyl-CpG-binding domain protein 4) belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2, MBD1, MBD2, and MBD4, except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MBD4  
  • Gene symbol
    MBD4
  • Short name
    MBD4 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    methyl-CpG binding domain protein 4 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    methyl-CpG binding domain protein 4, MED1, MBD4 and IDBG-55837 and ENSG00000129071 and 8930, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, nuclei, Mbd4 and IDBG-179645 and ENSMUSG00000030322 and 17193, BT.49400 and IDBG-646370 and ENSBTAG00000021645 and 511463
Gene info
  • Identity
  • Gene
  • Long gene name
    methyl-CpG binding domain 4, DNA glycosylase
  • Synonyms gene name
    • methyl-CpG binding domain protein 4
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1999-01-11
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • DNA glycosylases
    • Methyl-CpG binding domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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