Anti-Lymphocyte Activation Gene 3, ALEXA Fluor 594

  • Catalog number
    GENTObs-2646R-A594
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    Lymphocyte Activation Gene 3
  • Specificity
    This antibody reacts specifically with Lymphocyte Activation Gene 3
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Extracellular
  • Antigen Source
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
  • Gene ID
    297596
  • Swiss Prot
    Q5BK54
  • Applications
    FCM, IF(IHC-P), IF(ICC)
  • Applications with corresponding dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    CD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3
  • Also known as
    Lymphocyte Activation Gene 3 Antibody
  • Other name
    Anti-Lymphocyte Activation Gene 3
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
  • Gene target
  • Gene symbol
    LAG3
  • Short name
    Anti-Lymphocyte Activation Gene 3
  • Technique
    activation, anti-, anti, antibody to, antibodies
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    Lymphocyte Activation Gene 3 Antibody, ALEXA FLUOR® 594 Conjugated
  • Alternative technique
    antibodies
  • Tissue
    lymphocyte
Gene info
  • Identity
  • Gene
  • Long gene name
    lymphocyte activating 3
  • Synonyms gene name
    • lymphocyte-activation gene 3
  • Synonyms
  • Locus
  • Discovery year
    1991-06-03
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin like domain containing
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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