anti-LRRTM3 Antibody
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Catalog number6171
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoLRRTM3 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
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Gene namesLRRTM3 Antibody: Leucine-rich repeat transmembrane neuronal protein 3
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Antibodie s labelunlabelled serum
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PurityLRRTM3 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toAt least two isoforms of LRRTM3 are known to exist; this antibody will only detect the larger isoform.
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AntigenLRRTM3 antibody was made against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceLRRTM3 antibody can be used for detection of LRRTM3 by Western blot at 0.5 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideLRRTM3 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atLRRTM3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr109809759
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Ncbi nrNP_821079
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr347731
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GENE symbolLRRTM3
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Antigene nameleucine rich repeat transmembrane neuronal 3
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SourceHomo sapiens
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Protein nrQ86VH5
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLRRTM3
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Short nameanti-LRRTM3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toLRRTM3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameleucine rich repeat transmembrane neuronal 3
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GenBank acession
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Locus
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Discovery year2004-02-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data