KIBRA Antibody, ALEXA FLUOR 594

• Catalog number
  bs-11570R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  KIBRA Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-KIBRA PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KIBRA
• Specificity
  This is a highly specific antibody against KIBRA.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  370-420/1113
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KIBRA
• Gene ID Number
  23286
• Swiss Prot
  Q8IX03
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  KIBRA; HBEBP3; HBEBP36; MEMRYQTL; PPP1R168; Protein KIBRA; HBeAg-binding protein 3; Kidney and brain protein; WW domain-containing protein 1; WWC1; KIAA0869
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  KIBRA  
• Gene symbol
  WWC1
• Short name
  Anti-KIBRA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  KIBRA Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29435
• Gene
  WWC1
• Long gene name
  WW and C2 domain containing 1
• Synonyms gene name
  • WW, C2 and coiled-coil domain containing 1
• Synonyms
  • KIBRA
  • KIAA0869
  • PPP1R168
• Synonyms name
  • protein phosphatase 1, regulatory subunit 168
• GenBank acession
  • AF506799
• Locus
  5q34
• Discovery year
  2006-02-22
• Entrez gene record
  23286
• Pubmed identfication
  • 10048485
  • 12559952
• RefSeq identity
  • NM_015238
• Classification
  • C2 and WW domain containing
  • WWC family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000130408

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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