Anti-Ki-67 (Proliferation Marker), ALEXA Fluor 594

  • Catalog number
    GENTObs-2130R-A594
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    Ki-67 proliferation Marker
  • Specificity
    This antibody reacts specifically with Ki-67 (Proliferation Marker)
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Nucleus
  • Antigen Source
    KLH conjugated synthetic peptide derived from human Ki67
  • Gene ID
    4288
  • Swiss Prot
    P46013
  • Applications
    IF(IHC-P), IF(ICC)
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67
  • Also known as
    Ki-67 (Proliferation Marker) Antibody
  • Other name
    Anti-Ki-67 (Proliferation Marker)
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Gene target
  • Gene symbol
    MKI67P1, MKI67
  • Short name
    Anti-Ki-67 (Proliferation Marker)
  • Technique
    anti-, anti, antibody to, antibodies, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    Ki-67 (Proliferation Marker) Antibody, ALEXA FLUOR® 594 Conjugated
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    marker of proliferation Ki-67 pseudogene 1
  • Synonyms gene name
    • antigen identified by monoclonal antibody Ki-67 pseudogene 1
  • Locus
  • Discovery year
    2013-10-10
  • Entrez gene record
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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