anti-JMJD2B Antibody
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Catalog number5375
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoJMJD2B Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. Like other members of the JMJD1 and JMJD2 families, JMJD2B is a histone demethylase, but is reported to be a very poor enzyme. Similar to JMJD1A, JMJD2B is a transcriptional target of the hypoxia-inducible factor (HIF), and hypoxic cells express elevated levels of the JMJD2B mRNA and protein. Both JMJD1A and JMJD2B retain their histone demethylase activity in hypoxic conditions, suggesting that this activity of JMJD2B might play a role in the hypoxic gene expression program.
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Gene namesJMJD2B Antibody: JMJD2B, TDRD14B, JHDM3B, JMJD2B, KIAA0876, Lysine-specific demethylase 4B, JmjC domain-containing histone demethylation protein 3B
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Antibodie s labelunlabelled serum
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PurityJMJD2B Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenJMJD2B antibody was made against a 16 amino acid synthetic peptide from near the center of human JMJD2B.
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Immuno applicationELISA, Western Blot
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Antibody adviceJMJD2B antibody can be used for detection of JMJD2B by Western blot at 1 - 2 ug/mL.
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Suspention pH azideJMJD2B Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atJMJD2B antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr223460136
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Ncbi nrAAI36612
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr23030
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GENE symbolKDM4B
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Antigene namelysine (K)-specific demethylase 4B
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SourceHomo sapiens
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Protein nrO94953
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolKDM4B
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Short nameanti-JMJD2B Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toJMJD2B (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelysine demethylase 4B
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Synonyms gene
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Synonyms gene name
- jumonji domain containing 2B
- lysine (K)-specific demethylase 4B
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-01-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tudor domain containing
- Lysine demethylases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data