JARID2 polyclonal antibody

• Catalog number
  6856-50
• Price
  Please ask
• Size
  50 μl

• Antibody Target
  JARID2
• Target Alternative Name
  JMJ
• Antibody Type
  Polyclonal
• Species Reactivities
  Human.
• Immunogen Sequence
  Polyclonal antibody raised in rabbit against human JARID2 (jumonji, AT rich interactive domain 2) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively.
• Accession
  Q92833
• Gene Id
  3720
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS with 0.05% (W/V) sodium azide.
• Purification
  Whole Anti-Sera
• Application
  ELISA.
• Positive Control
  ELISA: Peptides.
• Application And Usages
  ELISA: 1:500.
• Description
  JARID2 is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. JARID2 acts by recruiting histone methyltransferase complexes (PRC2) to their target genes and modulating the histone methyltransferase activity. It does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of H3K27me3 by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating H3K9 methylation by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  JARID2  
• Gene symbol
  JARID2-AS1, JARID2-DT, JARID2
• Short name
  JARID2 polyclonal antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  jumonji, AT rich interactive domain 2 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  jumonji, AT rich interactive domain 2, JMJ, JARID2 and IDBG-62820 and ENSG00000008083 and 3720, protein binding, nuclei, Jarid2 and IDBG-147776 and ENSMUSG00000038518 and 16468, JARID2 and IDBG-636025 and ENSBTAG00000012938 and 528253

Gene info

• Identity
  HGNC:40314
• Gene
  JARID2-AS1
• Long gene name
  JARID2 antisense RNA 1
• Synonyms gene name
  • JARID2 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AW340306
  • AW665239
• Locus
  6p22.3
• Discovery year
  2011-12-05
• Entrez gene record
  100506681
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000014292

Gene info

• Identity
  HGNC:55240
• Gene
  JARID2-DT
• Long gene name
  JARID2 divergent transcript
• Locus
  6p22.3
• Discovery year
  2020-09-16
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:6196
• Gene
  JARID2
• Long gene name
  jumonji and AT-rich interaction domain containing 2
• Synonyms gene
  • JMJ
• Synonyms gene name
  • jumonji (mouse) homolog
  • Jumonji, AT rich interactive domain 2
  • jumonji, AT rich interactive domain 2
• GenBank acession
  • U57592
• Locus
  6p22.3
• Discovery year
  1997-09-05
• Entrez gene record
  3720
• Pubmed identfication
  • 8894700
• RefSeq identity
  • NM_004973
• Classification
  • Iron (II) and 2-oxoglutarate dependent oxygenases
  • AT-rich interaction domain containing
• VEGA ID
  OTTHUMG00000014293

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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