Jarid1c polyclonal antibody
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Catalog number
6855-50
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Price
Please ask
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Size
50 μl
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Antibody Target
Jarid1c
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Target Alternative Name
KDM5C, MRXJ, MRXSJ, SMCX, XE169
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Antibody Type
Polyclonal
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Species Reactivities
Human, mouse.
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Immunogen Sequence
Polyclonal antibody raised in rabbit against mouse Jarid1c (jumonji, AT rich interactive domain 1C), using 3 KLH-conjugated synthetic peptides containing sequences from the inner part of the protein.
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Accession
P41229
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Gene Id
8242
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In PBS with 0.05% (W/V) sodium azide.
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Purification
Whole Anti-Sera
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Application
Western blot, ELISA.
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Positive Control
Western blot: HeLa cells, ELISA: Peptides.
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Application And Usages
Western Blot: 1:1000, ELISA: 1:500.
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Description
Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a central role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
KDM5C
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Short name
Jarid1c polyclonal antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Isotype
Rabbit IgG
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Alternative name
Jarid1c polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene name
lysine demethylase 5C
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Synonyms gene
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Synonyms gene name
- Jumonji, AT rich interactive domain 1C (RBP2-like)
- Smcy homolog, X-linked (mouse)
- jumonji, AT rich interactive domain 1C
- mental retardation, X-linked 13
- lysine (K)-specific demethylase 5C
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-04-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- PHD finger proteins
- Lysine demethylases
- AT-rich interaction domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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