anti-IKK epsilon Antibody

• Catalog number
  2329
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  IKK epsilon Antibody: Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa;, IKKβ, and IKKγ. A novel molecule in the IKK complex was recently identified and designated IKKε/IKK-i. IKK epsilon is required for the activation of NF-kB by PMA and T cell receptors but not by TNFa; and IL-1. IKKε/IKK-i message is expressed in a variety of tissues and is inducible by TNFa;, IL-1, and LPS.
• Gene names
  IKK epsilon Antibody: IKKE, IKKI, IKK-E, IKK-i, IKKE, KIAA0151, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, Inducible I kappa-B kinase, I-kappa-B kinase epsilon
• Antibodie s label
  unlabelled serum
• Purity
  IKK epsilon Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  It has no cross response to IKKa, IKKb, or IKKy.
• Antigen
  IKK epsilon antibody was made against a 16 amino acid peptide near the carboxy terminus of human IKK epsilon.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  IKK epsilon antibody can be used for detection of IKK epsilon by Western blot at 1 ug/mL. An 80 kDa band should be detected. Antibody can also be used for immunohistochemistry starting at 10 ug/mL.
• Suspention pH azide
  IKK epsilon Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  IKK epsilon antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  7288877
• Ncbi nr
  AF241789
• KDa
  80 kDa
• Vial with antibody
  in solution
• NCBI GENE nr
  9641
• GENE symbol
  IKBKE
• Antigene name
  inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
• Source
  Homo sapiens
• Protein nr
  Q14164
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IKK   epsilon  
• Gene symbol
  IKBKE, IKBKB, CHUK, IKBKG
• Short name
  anti-IKK epsilon Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIKK epsilon (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14552
• Gene
  IKBKE
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit epsilon
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
• Synonyms
  • IKKE
  • IKK-i
  • KIAA0151
• GenBank acession
  • AB016590
• Locus
  1q32.1
• Discovery year
  2002-12-02
• Entrez gene record
  9641
• Pubmed identfication
  • 10421793
  • 10882136
• Classification
  • I kappa B kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000184613

Gene info

• Identity
  HGNC:5960
• Gene
  IKBKB
• Long gene name
  inhibitor of nuclear factor kappa B kinase subunit beta
• Synonyms gene name
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• Synonyms
  • IKK2
  • NFKBIKB
  • IKK-beta
  • IKKB
• GenBank acession
  • AF029684
• Locus
  8p11.21
• Discovery year
  1998-02-11
• Entrez gene record
  3551
• Pubmed identfication
  • 9878263
  • 9763654
  • 18308615
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000164092
• Locus Specific Databases
  • LRG_1241

Gene info

• Identity
  HGNC:1974
• Gene
  CHUK
• Long gene name
  component of inhibitor of nuclear factor kappa B kinase complex
• Synonyms gene
  • TCF16
• Synonyms gene name
  • conserved helix-loop-helix ubiquitous kinase
• Synonyms
  • IKK1
  • IKK-alpha
  • IkBKA
  • NFKBIKA
  • IKKA
• Synonyms name
  • inhibitor of nuclear factor kappa-B kinase subunit alpha
  • I-kappa-B kinase
• GenBank acession
  • AF009225
• Locus
  10q24.31
• Discovery year
  1995-03-15
• Entrez gene record
  1147
• Pubmed identfication
  • 7558004
  • 16902410
• RefSeq identity
  • NM_001278
• Classification
  • I kappa B kinases
  • IKK complex
• VEGA ID
  OTTHUMG00000018899

Gene info

• Identity
  HGNC:5961
• Gene
  IKBKG
• Long gene name
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
• Synonyms gene
  • IP2
  • IP1
• Synonyms gene name
  • incontinentia pigmenti
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • inhibitor of nuclear factor kappa B kinase subunit gamma
• Synonyms
  • IKK-gamma
  • NEMO
  • Fip3p
  • FIP-3
  • FIP3
  • ZC2HC9
  • IKKAP1
  • IKKG
• Synonyms name
  • NF-kappa-B essential modulator
  • IkB kinase-associated protein 1
  • I-kappa-B kinase subunit gamma
  • IkB kinase subunit gamma
  • 14.7K (adenovirus E3 protein) interacting protein 3
• GenBank acession
  • AF074382
• Locus
  Xq28
• Discovery year
  1998-09-30
• Entrez gene record
  8517
• Pubmed identfication
  • 9751060
  • 10087442
  • 11590134
  • 11242109
• RefSeq identity
  • NM_003639
• Classification
  • Zinc fingers C2HC-type
  • IKK complex
• VEGA ID
  OTTHUMG00000024234
• Locus Specific Databases
  • IKBKGbase: Mutation registry for Nemo deficiency
  • Global Variome shared LOVD
  • LRG_70

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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