OVA Conjugated Interleukin 6 (IL6)
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Catalog number
CPA079Cp21
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Price
Please ask
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Size
500ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Capra hircus; Caprine (Goat)
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Item Name
Interleukin 6
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Alternative Names
MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor
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Research Area
Cytokine;Tumor immunity;Infection immunity;Cardiovascular biology;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
Pro165-Glu180
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Tag
N-terminal His Tag
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Expression System
Protein conjugation
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Application
Immunogen; SDS-PAGE; WB.
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Gene
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Recombinant, rec. E. coli interleukin-6 for cell culture or antibody production. Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
IL6-AS1, IL6, CEBPD
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Short name
OVA Conjugated Interleukin 6 (IL6)
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Technique
antibody Conjugates
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Host
Protein conjugation
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Species
Capra hircus; Caprine (Goat)
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Alternative name
OVA coupled Interleukin 6 (interleukin 6 (interferon, beta 2))
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Alternative to gene target
interleukin 6 (interferon, beta 2), BSF2 and HGF and HSF and IFNB2 and IL-6, IL6 and IDBG-9462 and ENSG00000136244 and 3569, growth factor activity, Extracellular, Il6 and IDBG-144970 and ENSMUSG00000025746 and 16193, IL6 and IDBG-630280 and ENSBTAG00000014921 and 280826
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Gene info
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Identity
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Gene
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Long gene name
IL6 antisense RNA 1
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Locus
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Discovery year
2019-08-14
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
interleukin 6
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Synonyms gene
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Synonyms gene name
- interleukin 6 (interferon, beta 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
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VEGA ID
Gene info
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