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Alternative name1
Anti-RABBIT ANTI HUMAN RAD17 (pSer645)
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Alternative name2
RABBIT ANTI HUMAN RAD17 (pSer645)
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Alternative name3
Lapin ANTI Homo sapiens RAD17 (pSer645)
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Alternative name4
RAD17
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Alternative name5
N/A
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Other names
cell cycle checkpoint protein RAD17 isoform 1; Cell cycle checkpoint protein RAD17; cell cycle checkpoint protein RAD17; RAD1 homolog; Rad17-like protein; RF-C activator 1 homolog; RF-C/activator 1 homolog; RAD17 homolog (S. pombe); RF-C/activator 1 homolog
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Gene name
RAD17
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Gene name synonims
N/A
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Other gene names
RAD17; RAD17; CCYC; R24L; RAD24; HRAD17; RAD17SP; R24L; hRad17
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Human
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Specificity and cross reactivity
RAD17 This item is specific for human RAD17 which is phosphorylated at Ser645. RAD17 is a cell cycle checkpoint protein required for activation of checkpoint signaling pathways in response to stalled replication forks and DNA damage. RAD17 is phosphorylated on Ser635 and Ser645 is response to DNA damage and replication inhibitors. Phosphorylation at these residues is also reported in undamaged cycling cells during S and G2/M
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 1.0 mg/ml
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Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested for
Western Blot (WB)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
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French translation
anticorps