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Products_type
Antibody
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Products_short_name
[KRT18 / CK18 / Cytokeratin 18]
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Products_name_syn
[Anti-KRT18 / CK18 / Cytokeratin 18 Antibody (aa381-430) IHC-plus; KRT18; CK-18; Cytokeratin 18; Cytokeratin-18; K18; Keratin 18; CYK18; Keratin-18; Human KRT18; CK18; Cytokeratin 18]
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Other_names
[keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18]
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Products_gene_name
[KRT18]
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Other_gene_names
[KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Keratin 18 Antibody detects endogenous levels of total Keratin 18 protein.
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Purity
Immunoaffinity Purified
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Form
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
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Concentration
1 mg/ml
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
KRT18
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Short name
Rabbit Polyclonal (IgG) KRT18 / CK18 / Cytokeratin 18
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Technique
Polyclonal, Rabbit, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal (Immunoglobulin G) to H. sapiens keratin 18 / CK18 / Cytokeratin 18
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Alternative technique
polyclonals, rabbit-anti, immunoglobulins
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Alternative to gene target
keratin 18, CYK18 and K18, KRT18 and IDBG-35299 and ENSG00000111057 and 3875, scaffold protein binding, nuclei, Krt18 and IDBG-187416 and ENSMUSG00000023043 and 16668, KRT18 and IDBG-631626 and ENSBTAG00000001517 and 506480
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