NFkB, p65 (NF-kB, Nuclear Factor kappa B, MGC131774, NFKB3, Nuclear Factor NF-Kappa-B p65, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A) (DyL Antibody

  • Catalog number
    GEN609872
  • Price
    Please ask
  • Size
    100ul
  • Also known as
    NFkB, p65
  • Other names
    NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c; NF-kappa-B inhibitor-interacting Ras-like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; I-kappa-B-interacting Ras-like protein 2
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
  • Gene name synonims
    NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
  • Other gene names
    NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG
  • Clone
    10J108
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes both phosphorylated and non-phosphorylated versions of human NF-kappa-B protein.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Purified
  • Form Appearance
    Supplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.02% sodium azide. Labeled with DyLight® 488.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Dylight® conjugates are sensitive to light.
  • Tested applications
    Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene
    NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
  • French translation
    anticorps
  • Gene target
    NFkB   p65   NF-kB   Factor   kappa   MGC131774   NFKB3   Factor   NF-Kappa-B   p65   Factor   Kappa   Light   Polypeptide   Gene   Enhancer   Cells   RelA   Transcription   Factor   p65   v-Rel   Avian   Reticuloendotheliosis   Viral   Oncogene   Homolog   DyL  
  • Gene symbol
    NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFATC2, NFYC, NFIL3
  • Short name
    NFkB, p65 (NF-kB, Factor kappa B, MGC131774, NFKB3, Factor NF-Kappa-B p65, Factor Of Kappa Light Polypeptide Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis Oncogene Homolog A) (DyL Antibody
  • Technique
    Antibody, light, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-NFkB, p65 (NF-kB, Nuclear Factor kappa B, MGC131774, NFKB3, Nuclear Factor NF-Kappa-B p65, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, RelA, Transcription Factor p65, v-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A) (DyL
  • Alternative technique
    antibodies
  • Alternative to gene target
    v-rel reticuloendotheliosis viral oncogene homolog (avian), C-Rel, REL and IDBG-53133 and ENSG00000162924 and 5966, sequence-specific DNA binding, nuclei, Rel and IDBG-155648 and ENSMUSG00000020275 and 19696, REL and IDBG-634277 and ENSBTAG00000015386 and 509135
  • Tissue
    cells
Gene info
Gene info
  • Identity
    HGNC:7780
  • Gene
    NFE2
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q13.13
  • Discovery year
    1993-11-03
  • Entrez gene record
    4778
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
    OTTHUMG00000169761
Gene info
Gene info
Gene info
  • Identity
    HGNC:6057
  • Gene
    INA
  • Long gene name
    internexin neuronal intermediate filament protein alpha
  • Synonyms gene
  • Synonyms gene name
    • internexin neuronal intermediate filament protein, alpha
  • Synonyms
  • GenBank acession
  • Locus
    10q24.33
  • Discovery year
    1999-03-24
  • Entrez gene record
    9118
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intermediate filaments Type IV
  • VEGA ID
    OTTHUMG00000018986
Gene info
Gene info
  • Identity
    HGNC:7775
  • Gene
    NFATC1
  • Long gene name
    nuclear factor of activated T cells 1
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
    • nuclear factor of activated T-cells 1
  • Synonyms
  • GenBank acession
  • Locus
    18q23
  • Discovery year
    1994-11-16
  • Entrez gene record
    4772
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nuclear factors of activated T-cells
    • IPT domain containing
  • VEGA ID
    OTTHUMG00000132897
Gene info
  • Identity
    HGNC:7776
  • Gene
    NFATC2
  • Long gene name
    nuclear factor of activated T cells 2
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    • nuclear factor of activated T-cells 2
  • Synonyms
  • GenBank acession
  • Locus
    20q13.2
  • Discovery year
    1994-11-16
  • Entrez gene record
    4773
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • IPT domain containing
    • Nuclear factors of activated T-cells
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000032747
Gene info
Gene info
MeSH Data
  • Name
    Blotting, Western
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
NFkB p65 NF kB Factor kappa B MGC131774 NFKB3 Factor NF Kapp
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