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Gene info
TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.
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Gene names
CVID, RYZN, TACI, CD267, CVID2, TNFRSF14B
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Antibodie s label
unlabelled serum
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Purity
Anti-hTACI specific antibody was purified by affinity chromatography employing immobilized hTACI matrix.
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Ab raised in
Goat
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Type
Polyclonal
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Antigen
Produced from sera of goats pre-immunized with highly pure (>98%) recombinant human TACI.
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Immuno application
ELISA, Western Blot
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Antibody advice
ELISA:To detect human TACI by direct ELISA (using 100 μL/well antibody solution) a concentration of at least 0.5 ug/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant human TACI.Sandwich:To detect hTACI by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 ug/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human TACI (XP-5278Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTACI. Western Blot:To detect human TACI by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant human TACI is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
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Keep at
TACI antibody is stable for at least 2 years from date of receipt at -20 grades C. The reconstituted antibody is stable for at least two weeks at 2-8 grades C. Frozen aliquots are stable for at least 6 months when stored at -20 grades C. Avoid repeated freeze-thaw cycles.
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Works with
Human
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Omim nr
121943629
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Ncbi nr
Q4ACX1
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Vial with antibody
Lyophilized
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NCBI GENE nr
23495
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GENE symbol
TNFRSF13B
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Antigene name
tumor necrosis factor receptor superfamily, member 13B
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Source
Homo sapiens
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Protein nr
Q4ACX1
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
