Rabbit Polyclonal to Human CASR/Calcium Sensing Receptor[CASR/Calcium Sensing Receptor]

• Catalog number
  MBS246716
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Products_gene_name
  [CASR]
• Reactivity
  Bat, Gibbon, Bovine, Chicken, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, RatPredicted Reactivity: Xenopus (at least 90% immunogen sequence identity)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  CASR/Calcium   Sensing   Receptor[CASR/Calcium   Sensing   Receptor]  
• Gene symbol
  CASR
• Short name
  Rabbit Polyclonal CASR/Calcium Sensing Receptor[CASR/Calcium Sensing Receptor]
• Technique
  Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  production species: rabbit polyclonal to H. sapiens CASR/Calcium Sensing Receptor[CASR/Calcium Sensing Receptor]
• Alternative technique
  polyclonals, rabbit-anti

Gene info

• Identity
  HGNC:1514
• Gene
  CASR
• Long gene name
  calcium sensing receptor
• Synonyms gene
  • HHC
  • HHC1
• Synonyms gene name
  • hypocalciuric hypercalcemia 1
  • calcium-sensing receptor
• Synonyms
  • FHH
  • NSHPT
  • GPRC2A
• Synonyms name
  • severe neonatal hyperparathyroidism
• GenBank acession
  • U20760
• Locus
  3q13.33-q21.1
• Discovery year
  1992-12-04
• Entrez gene record
  846
• Pubmed identfication
  • 7677761
• RefSeq identity
  • NM_000388
• Classification
  • Calcium sensing receptors
• VEGA ID
  OTTHUMG00000159491
• Locus Specific Databases
  • CASRdb Calcium Sensing Receptor Locus Mutation Database

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

Product images

Similar products