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Alternative name1
Anti-Rabbit Polyclonal (IgG) to Mouse CASP2 / Caspase 2
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Alternative name2
Rabbit PAb (IgG) to Murine CASP2 / Caspase 2
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Alternative name3
Lapin Polyclonal (IgG) to Mus musculus CASP2 / Caspase 2
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Alternative name4
CASP2 / Caspase 2
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Alternative name5
Anti-CASP2 / Caspase 2 Antibody IHC-plus; CASP2; CASP-2; Caspase-2; PPP1R57; Protease ICH-1; NEDD-2; Caspase 2; ICH1; NEDD2; Mouse CASP2; Caspase 2
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Other names
caspase-2 isoform 1 preproprotein; Caspase-2; caspase-2; protease ICH-1; protein phosphatase 1, regulatory subunit 57; neural precursor cell expressed developmentally down-regulated protein 2; caspase 2, apoptosis-related cysteine peptidase; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1Cleaved into the following 3 chains:Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12
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Gene name
CASP2
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Gene name synonims
N/A
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Other gene names
CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2; NEDD-2
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Human, Mouse, Rat
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Specificity and cross reactivity
Detects the full length and small subunit of caspase-2. In human samples, it also detects a 30 kD intermediate fragment. Mouse small intestine lysate can be used as a positive control.
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Purification method
Affinity Purified
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Form Appearance
PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.
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Concentration
0.2 mg/ml
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Storage and shipping
Long term: -70 degree C; Short term: Store productone at -20 degrees Celsius.
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Tested for
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
CASP2
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Short name
PAb (IgG) Mouse CASP2 / Caspase 2 Antibody
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Technique
Antibody, Mouse, IgG, antibodies against human proteins, antibodies for, IgGs, mouses
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Host
mouse
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Isotype
IgG, IgG
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Species
Mouse, Mouses
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Alternative name
polyclonal (Immunoglobulin G) to Mouse caspase 2, apoptosis-related cysteine peptidase / caspase 2 (antibody to-)
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Alternative technique
antibodies, murine, immunoglobulins
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Alternative to gene target
caspase 2, apoptosis-related cysteine peptidase, CASP-2 and ICH1 and NEDD-2 and NEDD2 and PPP1R57, CASP2 and IDBG-45836 and ENSG00000106144 and 835, cysteine-type endopeptidase activity involved in apoptotic process, nuclei, Casp2 and IDBG-141522 and ENSMUSG00000029863 and 12366, BT.103474 and IDBG-636898 and ENSBTAG00000018159 and 531419
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