Rabbit Polyclonal to Human CASP14 / Caspase 14
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Catalog number
MBS240456
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Price
Please ask
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Size
0.05 mg
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Products_type
Antibody
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Products_short_name
[CASP14 / Caspase 14]
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Products_name_syn
[Anti-CASP14 / Caspase 14 Antibody (C-Terminus) IHC-plus; CASP14; Caspase-14; Caspase 14; MICE; CASP-14; Human CASP14; Caspase 14]
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Other_names
[caspase-14; Caspase-14; caspase-14; CASP-14; apoptosis-related cysteine protease; caspase 14, apoptosis-related cysteine protease; caspase 14, apoptosis-related cysteine peptidase]
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Products_gene_name
[CASP14]
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Other_gene_names
[CASP14; CASP14; CASP-14]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
16 amino acid peptide from near the carboxy-terminus of human caspase-14
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Purity
Purified
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Form
PBS, 0.02% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
CASP14
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Short name
Rabbit Polyclonal CASP14 / Caspase 14
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Technique
Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal to H. sapiens caspase 14, apoptosis-related cysteine peptidase / caspase 14
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Alternative technique
polyclonals, rabbit-anti
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Alternative to gene target
caspase 14, apoptosis-related cysteine peptidase, CASP14 and IDBG-34154 and ENSG00000105141 and 23581, cysteine-type peptidase activity, nuclei, Casp14 and IDBG-169485 and ENSMUSG00000005355 and 12365, CASP14 and IDBG-642581 and ENSBTAG00000021106 and 517658
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Gene info
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Identity
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Gene
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Long gene name
caspase 14
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Synonyms gene name
- caspase 14, apoptosis-related cysteine protease
- caspase 14, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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Locus
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Discovery year
1998-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
Product images
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