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Products_type
Antibody
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Products_short_name
[C5AR1 / CD88 / C5a Receptor]
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Products_name_syn
[Anti-C5AR1 / CD88 / C5a Receptor Antibody (Internal) IHC-plus; C5AR1; C5A; C5a-R; C5a ligand; C5a receptor; CD88; C5a anaphylatoxin receptor; C5AR; C5R1; CD88 antigen; Human C5AR1; CD88; C5a Receptor]
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Other_names
[C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1; complement component 5a receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88]
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Products_gene_name
[C5AR1]
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Other_gene_names
[C5AR1; C5AR1; C5A; C5AR; C5R1; CD88; C5AR; C5R1; C5a-R; C5aR]
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Clonality
Polyclonal
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Reactivity
Chimpanzee, Gorilla, Human, Monkey, Orangutan
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Specificity
Human C5AR1 / CD88. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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Purity
Immunoaffinity Purified
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Form
PBS, 0.1% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
Long term: -70 degree C; Short term: +4 degree C
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Tested_application
Immunohistochemistry (IHC - Paraffin)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
C5AR1
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Short name
Rabbit Polyclonal C5AR1 / CD88 / C5a Receptor
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Technique
Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal to H. sapiens complement component 5a receptor 1 / CD88 / C5a Receptor
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Alternative technique
polyclonals, rabbit-anti
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Alternative to gene target
complement component 5a receptor 1, C5A and C5AR and C5R1 and CD88, C5AR1 and IDBG-59445 and ENSG00000197405 and 728, C5a anaphylatoxin receptor activity, Cell surfaces, C5ar1 and IDBG-146297 and ENSMUSG00000049130 and 12273, BT.34208 and IDBG-639986 and ENSBTAG00000020872 and 101908388,493645
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