anti-HS3ST5 Antibody
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Catalog number30-503
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PricePlease ask
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Size50 ug
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Gene infoHS3ST5 is the rate limiting enzyme for synthesis of HSact. It performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. HS3ST5 also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).
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Gene namesHS3ST5, 3-OST-5, 3OST5, HS3OST5, NBLA04021
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HS3ST5.
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Immuno applicationELISA, Western Blot
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Antibody adviceHS3ST5 antibody can be used for detection of HS3ST5 by ELISA at 1:1562500. HS3ST5 antibody can be used for detection of HS3ST5 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store HS3ST5 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman, Mouse, Rat
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Omim nr45267824
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Ncbi nrNP_705840
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KDa40 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr222537
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GENE symbolHS3ST5
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Antigene nameheparan sulfate (glucosamine) 3-O-sulfotransferase 5
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SourceHomo sapiens
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Protein nrQ8IZT8
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHS3ST6, HS3ST5
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Short nameanti-HS3ST5 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toheparan sulfate (glucosamine) 3-O-sulfotransferase 5 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetheparan sulfate (glucosamine) 3-O-sulfotransferase 5, HS3ST5 and IDBG-408918 and ENSG00000249853 and 222537, 3'-phosphoadenosine 5'-phosphosulfate binding, Plasma membranes, Hs3st5 and IDBG-143965 and ENSMUSG00000044499 and 319415, HS3ST5 and IDBG-631208 and ENSBTAG00000000188 and 540355
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Gene info
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Identity
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Gene
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Long gene nameheparan sulfate-glucosamine 3-sulfotransferase 6
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Synonyms gene
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Synonyms gene name
- heparan sulfate (glucosamine) 3-O-sulfotransferase 5
- heparan sulfate (glucosamine) 3-O-sulfotransferase 6
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Locus
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Discovery year2000-12-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sulfotransferases, membrane bound
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheparan sulfate-glucosamine 3-sulfotransferase 5
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Synonyms gene name
- heparan sulfate (glucosamine) 3-O-sulfotransferase 5
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sulfotransferases, membrane bound
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data