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Type
Conjugated Primary Antibody
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Conjugated with
ALEXA FLUOR® 594
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Host organism
Rabbit (Oryctolagus cuniculus)
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Target Protein Peptide
HIV2 gp41 + gp160
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Specificity
This antibody reacts specifically with HIV2 gp41 + gp160
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Modification
No modification has been applied to this antibody
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Modification site
None
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Clonality
Polyclonal Antibody
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Clone
Polyclonal Antibodies
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Concentration
1ug per 1ul
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Subcellular locations
N/A
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Antigen Source
KLH conjugated synthetic peptide derived from human HIV2 gp41 + gp160
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Gene ID
N/A
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Swiss Prot
N/A
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Applications
IF(IHC-P)
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Applications with corresponding dilutions
IF(IHC-P)(1:50-200)
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Cross reactive species
Virus
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Cross Reactive Species details
HIV2
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Background information
Human immunodeficiency virus type 2 (HIV2), orginally isolated from patients in West Africa, is the dominant form of HIV in West Africa capable of causing the acquired immunodeficiency syndrome (AIDS). HIV2 is closely related to simian immunodeficiency viruses (SIV). HIV1 and HIV2 share similarity in their genomes, transmission, clinical features, immunological effects, and in their action of binding to the same CD4 cellular receptor, but there are significant differences in the amino acid and nucleotide sequences of HIV1 and HIV2, especially within their envelope genes and proteins. Additionally, HIV2 may have a longer incubation period and may be less pathogenic than HIV1. HIV2 gp36 is a transmembrane protein located in the envelope of the virus specific to HIV2 that binds to the putative cellular receptor proteins P45 and P62.
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Purification method
Purified by Protein A.
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Storage
Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission
590nm/617nm
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Synonyms
Gp41; Gp160; HIV-2 gp41; HIV2 gp160; HIV2gp41; HIV2gp160; HIV 2; Human immunodeficiency virus 2; Human Immunodeficiency Virus Type 2; ENV_HV2RO.
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Also known as
HIV2 gp41 + gp160 Polyclonal Antibody
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Other name
Anti-HIV2 gp41 + gp160 Polyclonal
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Advisory
Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
For facs or microscopy Alexa 1 conjugate.
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Conjugation
Alexa Fluor, ALEXA FLUOR® 594
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Conjugated
Alexa conjugate 1
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
