HEXDC Antibody, ALEXA FLUOR 594
-
Catalog number
bs-8418R-A594
-
Price
Please ask
-
Size
100ul
-
-
Long name
HEXDC Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
-
Also known as
Anti-HEXDC PAb ALEXA FLUOR 594
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 594
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
HEXDC
-
Specificity
This is a highly specific antibody against HEXDC.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXDC
-
Gene ID Number
284004
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
590nm/617nm
-
Synonyms
Beta hexosaminidase D; Beta N acetylhexosaminidase; FLJ23825; Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing; hexosaminidase glycosyl hydrolase family 20, catalytic domain; Hexosaminidase D; Hexosaminidase domain containing protein; N acetyl beta galactosaminidase; HEXDC_HUMAN.
-
Properties
For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR® 594
-
Conjugated
Alexa conjugate 1
-
French translation
anticorps
-
Gene target
-
Gene symbol
HEXD, HEXD-IT1
-
Short name
Anti-HEXDC
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 594
-
Alternative name
HEXDC Polyclonal Antibody, ALEXA FLUOR 594
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
hexosaminidase D
-
Synonyms gene
-
Synonyms gene name
- hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2006-01-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
