Anti-Hemoglobin Beta (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-8554R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  Hemoglobin Beta
• Specificity
  This antibody reacts specifically with Hemoglobin Beta
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human Hemoglobin beta
• Gene ID
  3043
• Swiss Prot
  P68871
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Involved in oxygen transport from the lung to the various peripheral tissues. LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure. Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  CD113t-C; beta-globin; Hemoglobin subunit beta; Hemoglobin beta chain; HBB
• Also known as
  Hemoglobin Beta Polyclonal Antibody
• Other name
  Anti-Hemoglobin Beta Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  Hemoglobin   Beta  
• Gene symbol
  HBB, HBBP1
• Short name
  Anti-Hemoglobin Beta
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Hemoglobin Beta Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:4827
• Gene
  HBB
• Long gene name
  hemoglobin subunit beta
• Synonyms gene name
  • hemoglobin, beta
• Synonyms
  • CD113t-C
  • beta-globin
• GenBank acession
  • J00173
• Locus
  11p15.4
• Discovery year
  2001-06-22
• Entrez gene record
  3043
• Pubmed identfication
  • 2649166
• RefSeq identity
  • NM_000518
• Classification
  • Hemoglobin subunits
• VEGA ID
  OTTHUMG00000066678
• Locus Specific Databases
  • HbVar: A Database of Human Hemoglobin Variants and Thalassemias
  • The Globin Gene Server
  • LRG_1232

Gene info

• Identity
  HGNC:4828
• Gene
  HBBP1
• Long gene name
  hemoglobin subunit beta pseudogene 1
• Synonyms gene name
  • hemoglobin, beta pseudogene 1
• Synonyms
  • HBH1
  • HBHP
• GenBank acession
  • X02133
• Locus
  11p15.4
• Discovery year
  1988-10-01
• Entrez gene record
  3044
• Pubmed identfication
  • 2649166
  • 28624809
• RefSeq identity
  • NR_001589
• VEGA ID
  OTTHUMG00000066684

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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