HDAC5 Antibody

  • Catalog number
    3605-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    HDAC5
  • Target Alternative Name
    HD5 , FLJ90614 , KIAA0600 , NY-CO-9
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse, rat
  • Immunogen Sequence
    Synthetic peptide surrounding amino acid 575 of human HDAC-5
  • Accession
    Q9UQL6
  • Gene Id
    10014
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) affinity purified rabbit anti-HDAC5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Purification
    Affinity purified
  • Application
    Western blotting, Immunoprecipitation, Immunohistochemistry
  • Application And Usages
    Western blotting (0.5-4 µg/ml), Immunoprecipitation (20 µg/ml), and Immunohistochemistry (20 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~124 kDa HDAC5 with human and mouse samples, and in a lesser extent with rat samples. It does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 6, 7, 8, 9,10, and 11.
  • Description
    Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    HDAC5  
  • Gene symbol
    HDAC5
  • Short name
    HDAC5 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    histone deacetylase 5 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    histone deacetylase 5, HD5 and NY-CO-9, HDAC5 and IDBG-53295 and ENSG00000108840 and 10014, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac5 and IDBG-212520 and ENSMUSG00000008855 and 15184, HDAC5 and IDBG-640847 and ENSBTAG00000016254 and 504242
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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