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Gene info
Hax1b Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.
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Gene names
Hax1b Antibody: SCN3, HS1BP1, HCLSBP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1
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Antibodie s label
unlabelled serum
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Purity
Hax1b Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Spicific to
At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b.
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Antigen
Hax1b antibody was made against a 10 amino acid synthetic peptide near the amino terminus of human Hax1b.
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Immuno application
ELISA, Western Blot
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Antibody advice
Hax1b antibody can be used for detection of Hax1b by Western blot at 1 - 2 ug/mL.
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Suspention pH azide
Hax1b Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Hax1b antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
66363694
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Ncbi nr
NP_001018238
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
10456
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GENE symbol
HAX1
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Antigene name
HCLS1 associated protein X-1
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Source
Homo sapiens
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Protein nr
O00165
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
