anti-Hax1a Antibody [9G3D11]
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Catalog number
PM-4718
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
Hax1a Monoclonal Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.
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Gene names
Hax1a Antibody [9G3D11] : SCN3, HS1BP1, HCLSBP1
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Antibodie s label
unlabelled serum
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Purity
Hax1a Monoclonal Antibody is immunoaffinity chromotography purified IgG.
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
9G3D11
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Immunoglobulin
IgG3
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Antigen
Mouse monoclonal Hax1a antibody was made against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a.
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Immuno application
ELISA, Western Blot
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Antibody advice
Hax1a antibody can be used for detection of Hax1A by Western blot at 1 - 2 ug/mL.
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Suspention pH azide
Hax1a Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Hax1a monoclonal antibody can be stored at -20 grades C, stable for one year.
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Works with
Human, Rat
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Omim nr
13435356
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Ncbi nr
NP_006109
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
10456
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GENE symbol
HAX1
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Antigene name
HCLS1 associated protein X-1
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Source
Homo sapiens
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Protein nr
O00165
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-Hax1a Antibody [9G3D11]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toHax1a (antibody to-) [9G3D11]
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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