FOXO3a Antibody

• Catalog number
  3673-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  FOXO3a
• Target Alternative Name
  FOXO3A , 602681 , O43524 , AF6q21 , DKFZp781A0677 ,FKHRL1 , FKHRL1P2 , mgC12739 , mgC31925
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  Synthetic peptide corresponding to residues on the C-terminus of human FOXO3a
• Accession
  O43524
• Gene Id
  2309
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) affinity purified rabbit anti-FOXO3a polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunoprecipitation
• Application And Usages
  Western blotting (0.5-4 µg/ml). Jurkat cell lysate (Cat.# 2401-100) and rat liver or rat kidney tissue lysate can be used as a positive control. A ~75 kDa band should be detected.
• Description
  Mammalian forkhead members of the class O (FOXO) transcription factors, including FOXO1, FOXO3a, and FOXO4, are implicated in the regulation of a variety of cellular processes, including the cell cycle, apoptosis, DNA repair, stress resistance, and metabolism. FOXO proteins are negatively regulated by the phosphatidylinositol 3-kinase-Akt signaling pathway, which is activated by growth factors and cytokines. Recent studies indicate that the activities of FOXO proteins are also regulated by oxidative stress, which induces their phosphorylation, translocation to the nucleus, and acetylation-deacetylation. Similar to the tumor suppressor p53, FOXO is activated by stress and induces the expression of genes that contribute to cell-cycle arrest, sμggesting that it also functions as a tumor suppressor.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FOXO3a  
• Gene symbol
  FOXO3
• Short name
  FOXO3a Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  FOXO3a (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3821
• Gene
  FOXO3
• Long gene name
  forkhead box O3
• Synonyms gene
  • FKHRL1
  • FOXO3A
• Synonyms
  • AF6q21
  • FOXO2
• GenBank acession
  • AF032886
• Locus
  6q21
• Discovery year
  1998-03-23
• Entrez gene record
  2309
• Pubmed identfication
  • 9479491
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000015327

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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