anti-FOXO1 Antibody [7h3]
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Catalog number
48-645
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Price
Please ask
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Size
0.05 mg
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Gene info
This antibody recognizes human FKHR (Forehead in Rhabdomyosarcoma), a 70 Kd protein that is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a co-activator or a co-repressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C-terminus of the FKHR protein. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
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Gene names
FOXO1, FKHR, Forkhead in rhabdomyosarcoma, FOXO1A, FKH1, Forkhead box protein O1, Forkhead box protein O1A, Forkhead box O1, Forkhead box o1a, Forkhead domain protein fkhr
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Antibodie s label
unlabelled serum
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Purity
Protein G Column
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
[7h3]
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Immunoglobulin
IgG1
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Antigen
FOXO1 monoclonal antibody was made against amino acids 242 - 655 of FOXO1 (Human).
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Immuno application
Western Blot, immuno-histo-chemistry
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Antibody advice
FOXO1 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.
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Suspention pH azide
PBS, pH 7.2. No preservatives added.
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Keep at
Store FOXO1 antibody at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
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Works with
Human
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Omim nr
116241368
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Ncbi nr
Q12778
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Vial with antibody
in solution
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NCBI GENE nr
2308
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GENE symbol
FOXO1
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Antigene name
forkhead box O1
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Source
Homo sapiens
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Protein nr
Q12778
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
FOXO1
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Short name
anti-FOXO1 Antibody [7h3]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toFOXO1 (antibody to-) [7h3]
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Alternative technique
antibodies
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Alternative to gene target
forkhead box O1, FKH1 and FKHR and FOXO1A, FOXO1 and IDBG-26475 and ENSG00000150907 and 2308, protein phosphatase 2A binding, nuclei, Foxo1 and IDBG-143370 and ENSMUSG00000044167 and 56458, FOXO1 and IDBG-629639 and ENSBTAG00000044105 and 506618
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Gene info
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Identity
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Gene
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Long gene name
forkhead box O1
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Synonyms gene
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Synonyms gene name
- forkhead homolog in rhabdomyosarcoma
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Synonyms
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Locus
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Discovery year
1994-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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