anti-FNIP2 Antibody
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Catalog number5045
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoFNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
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Gene namesFNIP2 Antibody: FNIPL, MAPO1, FNIPL, KIAA1450, Folliculin-interacting protein 2, FNIP1-like protein
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Antibodie s labelunlabelled serum
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PurityFNIP2 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toMultiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
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AntigenFNIP2 antibody was made against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceFNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideFNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atFNIP2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr154689769
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Ncbi nrNP_065891
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr57600
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GENE symbolFNIP2
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Antigene namefolliculin interacting protein 2
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SourceHomo sapiens
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Protein nrQ9P278
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolFNIP2
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Short nameanti-FNIP2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toFNIP2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namefolliculin interacting protein 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2008-03-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DENN domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data