anti-FMR1 Antibody

• Catalog number
  7707
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Fragile X syndrome is a frequent form of inherited mental retardation caused by functional loss of the fragile X mental retardation protein, FMR1, also known as FMRP (1). FMR1 binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm (2). A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome (1). Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) (3).
• Gene names
  FMR1 Antibody: Fragile X mental retardation protein 1, FMRP
• Antibodie s label
  unlabelled serum
• Purity
  FMR1 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  FMR1 antibody is human, mouse and rat reactive. Multiple isoforms of FMR1 are known to exist.
• Antigen
  FMR1 antibody was made against a 19 amino acid peptide near the carboxy terminus of human FMR1.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  FMR1 antibody can be used for detection of FMR1 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  FMR1 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  FMR1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  4503765
• Ncbi nr
  NP_002015
• KDa
  Predicted: 70 kDa Observed: 74 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  2332
• GENE symbol
  FMR1
• Antigene name
  fragile X mental retardation 1
• Source
  homo sapiens
• Protein nr
  Q06787
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FMR1  
• Gene symbol
  FMR1-IT1, FMR1-AS1, FMR1
• Short name
  anti-FMR1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toFMR1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:41333
• Gene
  FMR1-IT1
• Long gene name
  FMR1 intronic transcript 1
• Synonyms gene name
  • FMR1 intronic transcript 1 (non-protein coding)
• Locus
  Xq27.3
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000046184

Gene info

• Identity
  HGNC:39081
• Gene
  FMR1-AS1
• Long gene name
  FMR1 antisense RNA 1
• Synonyms gene
  • FMR1AS
  • FMR1-AS
• Synonyms gene name
  • FMR1 antisense RNA (non-protein coding)
  • FMR1 antisense RNA 1 (non-protein coding)
  • FMR1 antisense RNA 1 (head to head)
• Synonyms
  • ASFMR1
  • FMR4
• Synonyms name
  • antisense fragile X mental retardation protein
• Locus
  Xq27.3
• Discovery year
  2010-10-05
• Entrez gene record
  100126270
• Pubmed identfication
  • 17921506
  • 18213394
• RefSeq identity
  • NR_024499
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000182466

Gene info

• Identity
  HGNC:3775
• Gene
  FMR1
• Long gene name
  FMRP translational regulator 1
• Synonyms gene
  • POF1
  • POF
• Synonyms gene name
  • premature ovarian failure 1
  • fragile X mental retardation 1
• Synonyms
  • FMRP
  • FRAXA
  • MGC87458
• GenBank acession
  • X69962
• Locus
  Xq27.3
• Discovery year
  1992-01-17
• Entrez gene record
  2332
• Pubmed identfication
  • 1572655
• RefSeq identity
  • NM_002024
• VEGA ID
  OTTHUMG00000022606
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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