anti-Fadd Antibody
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Catalog number27-306
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PricePlease ask
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Size50 ug
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Gene infoFadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
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Gene namesFadd, Mort1/FADD
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse Fadd.
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Immuno applicationELISA, Western Blot
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Antibody adviceFadd antibody can be used for detection of Fadd by ELISA at 1:62500. Fadd antibody can be used for detection of Fadd by western blot at 0.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store Fadd antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withMouse
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Omim nr6753812
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Ncbi nrNP_034305
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KDa23 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr14082
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GENE symbolFADD
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Antigene nameFas (TNFRSF6)-associated via death domain
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SourceMus musculus
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Protein nrQ61160
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCFLAR, FADD
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Short nameanti-Fadd Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toFadd (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetFas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
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Gene info
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Identity
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Gene
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Long gene nameCASP8 and FADD like apoptosis regulator
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Synonyms gene
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Synonyms gene name
- CASP8 and FADD-like apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFas associated via death domain
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Synonyms gene name
- Fas (TNFRSF6)-associated via death domain
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data