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Products_type
Antibody
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Products_short_name
[CASP8 and FADD-like apoptosis regulator]
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Products_name_syn
[CFLAR Antibody; CASP8 and FADD-like apoptosis regulator, Mouse Anti Human; CASP8 and FADD-like apoptosis regulator; Cellular FLICE-like inhibitory protein; Caspase-eight-related protein; Caspase-like apoptosis regulatory protein; MACH-related inducer of toxicity; Caspase homolog; Inhibitor of FLICE; FADD-like antiapoptotic molecule 1; Usurpin; c-FLIP; Casper; CLARP; MRIT; CASH; I-FLICE; FLAME-1; CFLAR; CASP8AP1]
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Other_names
[CASP8 and FADD-like apoptosis regulator isoform 6; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; FADD-like antiapoptotic molecule 1; MACH-related inducer of toxicity; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; cellular FLICE-like inhibitory protein; inhibitor of FLICE; usurpin beta; CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; UsurpinCleaved into the following 2 chains:CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
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Products_gene_name
[CFLAR]
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Other_gene_names
[CFLAR; CFLAR; CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1; CASH; CASP8AP1; CLARP; MRIT; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT]
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Clonality
Monoclonal
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Clone
[P5D8AT]
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Purity
CFLAR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
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Form
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
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Storage_stability
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
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Tested_application
ELISA (EIA), Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk. This 1 is suited for programmed cell-death studies.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
FADD, CASP8
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Short name
Mouse Anti CASP8 FADD-like apoptosis regulator
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Technique
anti human, apoptosis, Mouse, anti, antibody to, anti human antibodies, apoptosis pathway, mouses
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Host
Mouse
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Isotype
IgG3 heavy chain and kappa light chain
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Species
Human, Humans, Mouses
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Alternative name
Mouse antibody to H. sapiens caspase 8, apoptosis-related cysteine peptidase and Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like programmed cellular destruction regulator
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Alternative technique
celldeath, murine, antibodies
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Alternative to gene target
Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
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