anti-MDS1 Antibody

• Catalog number
  28-888
• Price
  Please ask
• Size
  100 ug

• Gene info
  MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
• Gene names
  MDS1, PRDM3, MDS1-EVI1
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MDS1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  MDS1 antibody can be used for detection of MDS1 by ELISA at 1:312500. MDS1 antibody can be used for detection of MDS1 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store MDS1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  255683386
• Ncbi nr
  NP_004982
• KDa
  19 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  4197
• GENE symbol
  MDS1
• Antigene name
  myelodysplasia syndrome 1
• Source
  Homo sapiens
• Protein nr
  Q13465
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MDS1  
• Gene symbol
  MECOM
• Short name
  anti-MDS1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMDS1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3498
• Gene
  MECOM
• Long gene name
  MDS1 and EVI1 complex locus
• Synonyms gene
  • MDS1
  • EVI1
• Synonyms gene name
  • myelodysplasia syndrome 1
  • ecotropic viral integration site 1
• Synonyms
  • MDS1-EVI1
  • PRDM3
  • KMT8E
• Synonyms name
  • PR domain 3
• GenBank acession
  • S82592
  • AF164154
• Locus
  3q26.2
• Discovery year
  1990-07-10
• Entrez gene record
  2122
• Pubmed identfication
  • 2115646
  • 8171026
  • 8643684
• RefSeq identity
  • NM_005241
  • NM_004991
• Classification
  • Lysine methyltransferases
  • Zinc fingers C2H2-type
  • PR/SET domain family
• VEGA ID
  OTTHUMG00000158596
• Locus Specific Databases
  • LRG_1118

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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