anti-EphrinB (phospho Tyr298) Antibody

• Catalog number
  50-222
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vancerhaeghen, 1998; Dufour et al., 2003; Oike et al., 2002). EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cellto cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific EphrinB residue (Tyr298) plays a key role in EphrinB signaling (Kalo, et al., 2001).
• Gene names
  CEK5, EPH-like kinase 5, EK5
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Phosphopeptide corresponding to amino acid residues surrounding the phosphoTyr298 of Xenopus EphrinB. Note: Xenopus Tyr298 is the homolog of human, mouse and rat Tyr317 and also chicken Tyr305.
• Immuno application
  Western Blot
• Antibody advice
  The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primate, Xenopus and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  EphrinB antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Dog, Zebrafish, Bovine, Chcicken, Xenopus
• Omim nr
  12230900
• Ncbi nr
  P28693
• KDa
  46
• Vial with antibody
  in solution
• NCBI GENE nr
  396513
• GENE symbol
  EPHB2
• Antigene name
  EPH receptor B2
• Source
  Gallus gallus
• Protein nr
  P28693
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EphrinB   phospho   Tyr298  
• Short name
  anti-EphrinB (phospho Tyr298) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toEphrinB (phosphorilated Tyr298) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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