Endostatin Antibody

• Catalog number
  5799-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Endostatin
• Target Alternative Name
  Endostatin-XV, Related to endostatin:Restin
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  E. coli-expressed recombinant human Endostatin
• Accession
  P39059
• Gene Id
  1306
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-human Endostatin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Recombinant human endostatin
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
• Description
  Endostatin has been identified as a C-terminal fragment of Collagen type 18, a recently identified member of a family of collagen-like proteins referred to as multiplexin family Endostatin specifically inhibits proliferation of endothelial cells althoμgh it does not affect the proliferation of EOMA cells. Endostatin also potently inhibits angiogenesis and tumor growth. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes. Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells, and endostatin treatment results in apoptosis of HUVE and HMVE cells.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Endostatin  
• Gene symbol
  COL18A1
• Short name
  Endostatin Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Endostatin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2195
• Gene
  COL18A1
• Long gene name
  collagen type XVIII alpha 1 chain
• Synonyms gene
  • KNO
• Synonyms gene name
  • Knobloch syndrome, type 1
  • collagen, type XVIII, alpha 1
• Synonyms
  • KS
  • KNO1
• Synonyms name
  • endostatin
• Locus
  21q22.3
• Discovery year
  1993-05-25
• Entrez gene record
  80781
• Pubmed identfication
  • 8188291
  • 8776601
  • 10942434
  • 17546652
• Classification
  • MicroRNA protein coding host genes
  • Collagens
• VEGA ID
  OTTHUMG00000090407

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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