-
Antibody Target
Elk-1
-
Target Alternative Name
ELK1, ELK 1, elk-1, Oncogene Elk1, ELK1 member of ETS oncogene family
-
Antibody Type
Polyclonal
-
Species Reactivities
Human, mouse, rat
-
Immunogen Sequence
Synthetic peptide surrounding amino acid 383 of human Elk-1
-
Accession
Contribute Send feedback
-
Gene Id
2002
-
Appearance
Colorless liquid
-
Form
Liquid
-
Concentration
0.5 mg/ml
-
Formulation
100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
-
Purification
Affinity purified
-
Application
Western blot
-
Application And Usages
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 62 kDa Elk-1 of human, mouse and rat origins.
-
Description
Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 (Ser383) is also a target of the stress-activated kinase SAPK/JNK.
-
Storage Condition
-20 °C
-
Shipping Condition
gel pack
-
Shelf Life
12 months
-
Usage
For Research Use Only! Not to be used in humans.
-
Handling
The antibody solution should be gently mixed before use.
-
Western Blot Verified
Verified
-
Immunocytochemistry Verified
Not Verified
-
Immunofluorescence Verified
Not Verified
-
Immunoprecipitation Verified
Not Verified
-
ELISA Verified
Not Verified
-
ChIP Verified
Not Verified
-
Flow Cytometry Verified
Not Verified
-