anti-PKR (Ab 451) Antibody
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Catalog number
79-399
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Price
Please ask
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Size
0.1 mg
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Gene info
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
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Gene names
PKR, PRKR, EIF2AK1, CBL2, RNF55, ADRB2, E2AK2, EIF2AK2, EIF2aK
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Antibodie s label
unlabelled serum
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Purity
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Ab raised in
Rabbit
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Type
Polyclonal
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Spicific to
This antibody detects endogenous level of total PKR protein.
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Antigen
PKR (Ab-451) antibody was made against a peptide sequence around aa.449~453 (K-G-T-L-R) derived from Human PKR.
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Immuno application
immuno-histo-chemistry, immuno fluorescence
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Antibody advice
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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Suspention pH azide
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Keep at
Store antibody at -20 grades C for up to one year.
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Works with
Human
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Omim nr
208431827
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Ncbi nr
NP_001129123.1
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KDa
68 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
5610
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GENE symbol
EIF2AK2
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Antigene name
eukaryotic translation initiation factor 2-alpha kinase 2
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Source
Homo sapiens
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Protein nr
P19525
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
EIF2AK2
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Short name
anti-PKR (Ab 451) Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toPKR (Antibody 451) (antibody to-)
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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