anti-EI24 Antibody
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Catalog number6487
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoEI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
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Gene namesEI24 Antibody: EPG4, PIG8, TP53I8, p53-induced gene 8 protein
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Antibodie s labelunlabelled serum
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PurityEI24 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toAt least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.
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AntigenEI24 antibody was made against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceEI24 antibody can be used for detection of EI24 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideEI24 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atEI24 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr55956766
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Ncbi nrNP_004870
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr9538
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GENE symbolEI24
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Antigene nameetoposide induced 2.4 mRNA
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SourceHomo sapiens
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Protein nrO14681
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolEI24
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Short nameanti-EI24 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toEI24 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetetoposide induced 2.4 mRNA, EPG4 and PIG8 and TP53I8, EI24 and IDBG-75495 and ENSG00000149547 and 9538, nuclei, Ei24 and IDBG-149508 and ENSMUSG00000062762 and 13663, BT.33239 and IDBG-642680 and ENSBTAG00000007202 and 532527
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Gene info
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Identity
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Gene
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Long gene nameEI24 autophagy associated transmembrane protein
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Synonyms gene name
- etoposide induced 2.4 mRNA
- etoposide induced 2.4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data