anti-EI24 Antibody

  • Catalog number
    6487
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    EI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
  • Gene names
    EI24 Antibody: EPG4, PIG8, TP53I8, p53-induced gene 8 protein
  • Antibodie s label
    unlabelled serum
  • Purity
    EI24 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.
  • Antigen
    EI24 antibody was made against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry
  • Antibody advice
    EI24 antibody can be used for detection of EI24 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
  • Suspention pH azide
    EI24 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    EI24 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    55956766
  • Ncbi nr
    NP_004870
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    9538
  • GENE symbol
    EI24
  • Antigene name
    etoposide induced 2.4 mRNA
  • Source
    Homo sapiens
  • Protein nr
    O14681
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    EI24  
  • Gene symbol
    EI24
  • Short name
    anti-EI24 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toEI24 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    etoposide induced 2.4 mRNA, EPG4 and PIG8 and TP53I8, EI24 and IDBG-75495 and ENSG00000149547 and 9538, nuclei, Ei24 and IDBG-149508 and ENSMUSG00000062762 and 13663, BT.33239 and IDBG-642680 and ENSBTAG00000007202 and 532527
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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